Browser specific design, while tempting, really isn't a good idea. For one thing, you're instantly limiting your audience. No matter how nicely you word your “this page works best in ” message, the fact* is that no one who wasn't related to the designer or forced to by IT has ever changed their browser because a web page didn't work in it.
No matter how much time you save in testing, you are ultimately doing your readers and clients a disservice by not making your web pages as browser agnostic as possible.
How to Write Browser Agnostic Web Pages
- Browser Specific Web Designs
- Designing Cutting Edge Web Sites
- Always Check Your Pages in Different Browsers
- Don't Tell Your Readers What Browser to Use
* Okay, yeah, I haven't tested this, but it stands to reason, right?